background:
This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]
Function:
May play a role in maintaining cell pluripotentiality.
Subcellular Location:
Nucleus. Cytoplasm.
Tissue Specificity:
Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors.
DISEASE:
Expressed in fetal ovary.
Database links:
Entrez Gene: 359787 Human
Entrez Gene: 73708 Mouse
Entrez Gene: 297576 Rat
Omim: 601688 Human
SwissProt: Q6W0C5 Human
SwissProt: Q8QZY3 Mouse
SwissProt: Q6IMK0 Rat
Unigene: 131358 Human
Unigene: 528118 Human
Unigene: 27982 Mouse
Unigene: 79056 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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