background:
CFDP1 is a 299 amino acid protein that is involved in embryogenesis and normal cell function. When treated with CFDP1 peptide, mouse molar teeth increase in size, whereas treating cells with antibodies against CFDP1 shows an increase in the number of apoptotic cells and gradual tooth disintegration. CFDP1 is highly expressed in developing mouse teeth and is expressed at lower levels in liver, lung and heart. The gene encoding CFDP1 maps to human chromsome 16, in a region that has been associated with inherited craniofacial diseases, such as fanconi anemia type A. There are two isoforms of CFDP1 that are produced as a result of alternative splicing events.
Function:
May play a role during embryogenesis (By similarity).
Tissue Specificity:
Ubiquitous.
Post-translational modifications:
Phosphorylated by CK2 (casein kinase II) in vitro.
Similarity:
Contains 1 BCNT-C domain.
Database links:
UniProtKB/Swiss-Prot: Q9UEE9.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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