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Rabbit Anti-ACN9/FITC Conjugated antibody
background:
SDHAF3 (Succinate Dehydrogenase Complex Assembly Factor 3) is a Protein Coding gene. Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Function:
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Subcellular Location:
Mitochondrion matrix
Similarity:
Belongs to the ACN9 family.
Belongs to the complex I LYR family. SDHAF3 subfamily.
Database links:
Entrez Gene: 57001 Human
Entrez Gene: 71238 Mouse
SwissProt: Q9NRP4 Human
SwissProt: Q8BQU3 Mouse
Unigene: 592269 Human
Unigene: 389086 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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