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Rabbit Anti-APOL5/FITC Conjugated antibody
background:
The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-V (apolipoprotein L-V), also known as APOL5, is a 433 amino acid protein that localizes to the cytoplasm and belongs to the apolipoprotein L family. Expressed in a variety of tissues including testis, stomach, uterus and skeletal muscle, apoL-V is thought to affect the movement of lipids in the cytoplasm and may allow the binding of lipids to organelles. Like other members of the apolipoprotein L family, apoL-V is thought to be involved in the development of schizophrenia.
Function:
Apolipoprotein L 5 is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.
Subcellular Location:
Cytoplasm (Probable).
Tissue Specificity:
Low level of expression; detected in uterus, testis, skeletal muscle and stomach.
Similarity:
Belongs to the apolipoprotein L family.
Database links:
Entrez Gene: 80831 Human
Omim: 607255 Human
SwissProt: Q9BWW9 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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