Rabbit Anti-BRD2/FITC Conjugated antibody

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BRD 2; Brd2; BRD2_HUMAN; Bromodomain containing 2; BROMODOMAIN CONTAINING PROTEIN2; Bromodomain-containing protein 2; D6S113E; DKFZp686N0336; female sterile homeotic related gene 1; FLJ31942; FSH; FSRG1; KIAA9001; NAT; O27.1.1; Really interesting new gene

Cat:

SL12888R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human BRD2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

88kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains two bromodomains and maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins are ubiquitously expressed.

Function:
May play a role in spermatogenesis or folliculogenesis.

Subunit:
Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.

Subcellular Location:
Nucleus.

Similarity:
Contains 2 bromo domains.
Contains 1 ET domain.

Database links:

Entrez Gene: 6046 Human

Entrez Gene: 14312 Mouse

Entrez Gene: 294276 Rat

Omim: 601540 Human

SwissProt: P2588 Human

SwissProt: Q7JJ13 Mouse

SwissProt: Q6MGA9 Rat

Unigene: 75243 Human

Unigene: 3444 Mouse

Unigene: 98146 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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