Function:
May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production.
Subunit:
When phosphorylated, interacts with LYN. Interacts with VAV1 and GRB2 (By similarity).
Tissue Specificity:
Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1.
Post-translational modifications:
Phosphorylation at Tyr-632 is induced by LPS (By similarity).
Similarity:
Belongs to the themis family.
Database links:
UniProtKB/Swiss-Prot: Q5TEJ8.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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