Rabbit Anti-DRIL1/FITC Conjugated antibody

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ARI3A_HUMAN; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain-containing protein 3A; AT-rich interactive domain-containing protein 3A; B cell regulator of IgH transcription; B-cell regulator of IgH transcription; Bright; dead ringer l

Cat:

SL13031R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DRIL1/ARID3A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

63kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

Function:
Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.

Subunit:
Homodimer. Heterodimer with ARID3B. Interacts with E2F1. Interacts with GTF2I and BTK.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between nucleus and cytoplasm.

Tissue Specificity:
Widely expressed, with highest expression in skeletal muscle, thalamus, and colon.

Similarity:
Contains 1 ARID domain.
Contains 1 REKLES domain.

Database links:

Entrez Gene: 1820 Human

Entrez Gene: 13496 Mouse

Entrez Gene: 314616 Rat

Omim: 603265 Human

SwissProt: Q99856 Human

SwissProt: Q62431 Mouse

Unigene: 501296 Human

Unigene: 301282 Mouse

nigene: 229683 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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