Rabbit Anti-DMWD/FITC Conjugated antibody

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dystrophia myotonica containing WD repeat motif; D19S593E; DM 9; DM9; DMR N9; DMR N9 protein; DMRN 9; DMRN9; DMWD; DMWD_HUMAN; Dystrophia myotonica containing WD repeat motif; Dystrophia myotonica containing WD repeat motif protein; Dystrophia myotonica W

Cat:

SL13042R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human DMWD/DMRN9

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

70kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.

Function:
Could have a regulatory function in meiosis.

Subcellular Location:
Contains 5 WD repeats.

Tissue Specificity:
Strongest expression in brain, liver, and testis. Also expressed in kidney and spleen.

Similarity:
Contains 5 WD repeats.

Database links:

Entrez Gene: 1762 Human

Omim: 609857 Human

SwissProt: Q09019 Human

Unigene: 515474 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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