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Rabbit Anti-FENS1/FITC Conjugated antibody
background:
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDFY1 (WD repeat and FYVE domain containing 1), also known as WDF1, FENS-1 or ZFYVE17, is a 410 amino acid protein that localizes to the early endosome and contains one FYVE-type zinc finger and seven WD repeats through which it may play a role in protein trafficking and signal transduction.
Subunit:
Binds PtdIns3P in vitro with high specificity over other phosphoinositides.
Subcellular Location:
Early endosome.
Similarity:
Contains 1 FYVE-type zinc finger.
Contains 7 WD repeats.
Database links:
Entrez Gene: 57590 Human
Entrez Gene: 69368 Mouse
Entrez Gene: 301549 Rat
SwissProt: Q8IWB7 Human
Unigene: 368359 Human
Unigene: 8557 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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