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Rabbit Anti-Giantin/FITC Conjugated antibody
background:
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010]
Function:
May participate in forming intercisternal cross-bridges of the Golgi complex.
Subunit:
Homodimer; disulfide-linked. Interacts with PLK3.
Subcellular Location:
Golgi apparatus membrane.
Database links:
Entrez Gene: 2801 Human
Entrez Gene: 99412 Mouse
Entrez Gene: 64528 Rat
Omim: 602580 Human
SwissProt: Q08379 Human
SwissProt: Q921M4 Mouse
SwissProt: Q62839 Rat
Unigene: 155827 Human
Unigene: 106376 Mouse
Unigene: 6165 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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