Rabbit Anti-GLT28D1/FITC Conjugated antibody

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ALG13; GLT28D1; ALG13_HUMAN; Asparagine linked glycosylation 13 homolog (S. cerevisiae); Asparagine-linked glycosylation 13 homolog; CXorf45; FLJ23018; FLJ31785; GLT28D1; Glycosyltransferase 28 domain containing protein 1; Glycosyltransferase 28 domain-co

Cat:

SL13380R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human GLT28D1/ALG13

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

126kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
ALG13 is a 1,137 amino acid protein belonging to the glycosyltransferase 28 family. Encoded by a gene that maps to human chromosome Xq23, ALG13 is a subunit of a bipartite UDP-N-acetylglucosamine transferase and plays a role in protein folding regulation and stabilization. ALG13 contains one OTU domain, one TudorSN domain, and exists as four alternatively spliced isoforms. Heterodimerizing with ALG14, ALG13 forms a UDP-GlcNAc glycosyltransferase, which catalyzes the second sugar addition of the oligosaccharide precursor in endoplasmic reticulum (ER) N-linked glycosylation. ALG13 localizes to ER and may be recruited to the cytosolic face of the membrane by interacting with ALG14.

Function:
Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway.

Subunit:
Isoform 2 may interact with ALG14.

Subcellular Location:
Endoplasmic reticulum. Could be recruited to the cytosolic face of the endoplasmic reticulum membrane through its interaction with ALG14.

Similarity:
Belongs to the glycosyltransferase 28 family.
Contains 1 OTU domain.
Contains 1 Tudor domain.

Database links:

Entrez Gene: 79868 Human

Omim: 300776 Human

SwissProt: Q9NP73 Human

Unigene: 443061 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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