Home > Product > Antibody > Rabbit Anti-ZBTB26/FITC Conjugated antibody
Bioref; KIAA1572; Zinc finger and BTB domain containing 26; Zinc finger and BTB domain containing protein 26; Zinc finger protein 481; Zinc finger protein 483; Zinc finger protein Bioref; ZNF481; ZBT26_HUMAN.
Cat:
SL13569R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human ZBTB26/ZNF481
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
50kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 26 (ZBTB26), also known as ZNF481, is a 441 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB26 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB26 functions as a transcription regulator.

Function:
ZBTB26 contains 4 C2H2-type zinc fingers. It may be involved in transcriptional regulation.

Subcellular Location:
Nuclear

Tissue Specificity:
Ubiquitous.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 4 C2H2-type zinc fingers.

Database links:

Entrez Gene: 57684 Human

Entrez Gene: 64633 Mouse

Entrez Gene: 311910 Rat

SwissProt: Q9HCK0 Human

Unigene: 5638 Human

Unigene: 383299 Mouse

Unigene: 211689 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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