Home
>
Product
>
Antibody
>
Rabbit Anti-ZBTB26/FITC Conjugated antibody
background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 26 (ZBTB26), also known as ZNF481, is a 441 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB26 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB26 functions as a transcription regulator.
Function:
ZBTB26 contains 4 C2H2-type zinc fingers. It may be involved in transcriptional regulation.
Subcellular Location:
Nuclear
Tissue Specificity:
Ubiquitous.
Similarity:
Contains 1 BTB (POZ) domain.
Contains 4 C2H2-type zinc fingers.
Database links:
Entrez Gene: 57684 Human
Entrez Gene: 64633 Mouse
Entrez Gene: 311910 Rat
SwissProt: Q9HCK0 Human
Unigene: 5638 Human
Unigene: 383299 Mouse
Unigene: 211689 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|