Rabbit Anti-ZBTB25/FITC Conjugated antibody

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ZBT25_HUMAN; ZBTB25; Zinc finger and BTB domain-containing protein 25; Zinc finger protein 46; Zinc finger protein KUP.

Cat:

SL13568R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZBTB25/ZNF46

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 25 (ZBTB25), also known as ZNF46 or KUP, is a 435 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus and expressed mainly in hematopoietic cells and testis, ZBTB25 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB25 functions as a transcription regulator.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed mainly in hematopoietic cells and testis.

Similarity:
Contains 1 BTB (POZ) domain.
Contains 2 C2H2-type zinc fingers.

Database links:

Entrez Gene: 7597 Human

Omim: 194541 Human

SwissProt: P24278 Human

Unigene: 654571 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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