Rabbit Anti-ZBED4/FITC Conjugated antibody

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Zinc finger BED domain containing 4; Zinc finger BED domain containing protein 4; Zinc finger BED type containing 4; ZBED4_HUMAN.

Cat:

SL13554R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZBED4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

130kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The zinc finger BED domain-containing protein family (ZBED) is comprised of ZBED1, ZBED2, ZBED3, ZBED4 and ZBED5. They each contain one BED-type zinc finger domains with the exception of ZBED4, which contain 4 BED-type zinc finger domains. ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoded genes by binding specifically to 5'-TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. ZBED3 is an Axin-binding protein involved in Wnt/beta-catenin signaling modulation. ZBED4 expression has been shown in human and mouse retinas where it is thought to act as a regulatory protein in cone photoreceptors and Müller cells. The functions of ZBED2 and ZBED5 have yet to be elucidated.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasmic and Nuclear

Tissue Specificity:
Widely expressed with highest levels in testis, kidney and spinal cord and brain corpus callosum. Expressed in the retina, found in the cone photoreceptors, Mueller cells, cone pedicles and in the innermost retinal layer.

Similarity:
Contains 4 BED-type zinc fingers.

Database links:

Entrez Gene: 9889 Human

Omim: 612552 Human

SwissProt: O75132 Human

Unigene: 475208 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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