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Rabbit Anti-ZBED3/FITC Conjugated antibody
Function:
Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression.
Subunit:
Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations.
Subcellular Location:
Cytoplasm. Membrane. Note=Colocalizes with AXIN1 in the cytoplasm.
Similarity:
Contains 1 BED-type zinc finger.
Database links:
Entrez Gene: 84327 Human
Entrez Gene: 72114 Mouse
Entrez Gene: 361881 Rat
SwissProt: Q96IU2 Human
Unigene: 584988 Human
Unigene: 3774 Mouse
Unigene: 103511 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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