background:
This gene encodes a sperm membrane protein that binds the zona pellucida of the egg in a species-specific manner. The encoded protein may be involved in signaling or gamete recognition. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Function:
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Subunit:
Probably forms covalent oligomers.
Subcellular Location:
Cell membrane. Exclusively on the apical region of the sperm head.
Tissue Specificity:
In testis, primarily in haploid spermatids.
Similarity:
Contains 1 EGF-like domain.
Contains 3 MAM domains.
Contains 4 TIL (trypsin inhibitory-like) domains.
Contains 5 VWFC domains.
Contains 4 VWFD domains.
Database links:
UniProtKB/Swiss-Prot: Q9Y493.4
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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