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Rabbit Anti-C9orf98/FITC Conjugated antibody
background:
Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf98 gene maps to human chromosome 9q34.13. Consisting of 479 amino acids, C9orf98 exists as two alternatively spliced isoforms and belongs to the adenylate kinase family.
Function:
Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP.
Subcellular Location:
Cytoplasm, cytosol.
Similarity:
Belongs to the adenylate kinase family.
Database links:
Entrez Gene: 31667 Human
SwissProt: Q96MA6 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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