Rabbit Anti-C9orf89/FITC Conjugated antibody

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Bcl10 interacting protein with CARD protein; BinCARD; Chromosome 9 open reading frame 89; BINCA_HUMAN.

Cat:

SL15346R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human C9orf89

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

26kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
C9orf89 plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. It may inhibit the phosphorylation of BCL10 in a CARD-dependent manner. There are two isoforms.

Function:
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.

Subunit:
Associates with BCL10 by CARD-CARD interaction.

Subcellular Location:
Nucleus. Note=Co-expression with BCL10 induced translocation from nucleus to cytosol.

Tissue Specificity:
Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.

Post-translational modifications:
Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 CARD domain.

Database links:

Entrez Gene: 84270 Human

SwissProt: Q96LW7 Human

Unigene: 434213 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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