Rabbit Anti-GPR70/FITC Conjugated antibody

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G protein coupled receptor 70; G protein-coupled receptor 70; G-protein coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148;GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); seven transmembrane helix receptor; Sweet taste

Cat:

SL15373R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human GPCR TAS1R1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

91kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Function:
Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.

Subunit:
Forms heterodimers with TAS1R3.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.

Database links:

Entrez Gene: 80835 Human

Entrez Gene: 110326 Mouse

Entrez Gene: 29407 Rat

Omim: 606225 Human

SwissProt: Q7RTX1 Human

SwissProt: Q99PG6 Mouse

SwissProt: Q9Z0R8 Rat

Unigene: 124574 Human

Unigene: 29232 Mouse

Unigene: 92309 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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