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Home > Product > Antibody > Rabbit Anti-HECTD3/FITC Conjugated antibody
HECT; HECT domain containing protein 3; Probable E3 ubiquitin protein ligase HECTD3; HECD3_HUMAN.
Cat:
SL15448R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human HECTD3
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
97kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).

Subunit:
Interacts with TRIOBP. Interacts with STX8 (By similarity).

Subcellular Location:
Cytoplasm, perinuclear region (By similarity).

Similarity:
Contains 1 DOC domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.

Database links:

Entrez Gene: 79654 Human

SwissProt: Q5T447 Human

Unigene: 525084 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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