Rabbit Anti-HERPUD2/FITC Conjugated antibody

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FLJ22313; FLJ31032; HERP2_HUMAN; HERPUD 2; HERPUD family member 2; HERPUD2; Homocysteine inducible endoplasmic reticulum stress inducible ubiquitin like domain member 2; Homocysteine responsive endoplasmic reticulum resident ubiquitin like domain member 2

Cat:

SL15465R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human HERPUD2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The endoplasmic reticulum (ER) stress response is triggered by the accumulation of unfolded proteins within the ER and is characterized by three events: the inhibition of translation (to prevent further protein accumulation), the up-regulated expression of polypeptide-folding proteins (known as the unfolded protein response or UPR) and the degradation of misfolded proteins by the ER-associated protein degradation (ERAD) system. Members of the homocysteine-inducible and ER stress-inducible ubiquitin-like domain families are components of the ERAD system and, via their ubiquitin-like domain, are thought to be involved in the destruction of misfolded proteins. HERPUD2 (Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2) is a 406 amino acid single-pass membrane protein containing one N-terminal ubiquitin-like domain. HERPUD2 is thought to be involved in the unfolded protein response (UPR) pathway.

Function:
Could be involved in the unfolded protein response (UPR) pathway (By similarity).

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Similarity:
Contains 1 ubiquitin-like domain.

Database links:

Entrez Gene: 64224 Human

Entrez Gene: 80517 Mouse

Entrez Gene: 300463 Rat

SwissProt: Q9BSE4 Human

SwissProt: Q9JJC9 Mouse

SwissProt: Q66HH4 Rat

Unigene: 643051 Human

Unigene: 142843 Mouse

Unigene: 231721 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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