Rabbit Anti-MYPN/FITC Conjugated antibody

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145 kDa sarcomeric protein; MYOP; Myopalladin; MYPN; MYPN_HUMAN; sarcomeric protein myopalladin.

Cat:

SL10366R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human MYPN

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

145kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
MYPN is a component of the sarcomere that tethers nebulin (MIM 161650) in skeletal muscle and nebulette (MIM 605491) in cardiac muscle to alpha-actinin (see ACTN2; MIM 102573) at the Z lines (Bang et al., 2001 [PubMed 11309420]).[supplied by OMIM, Mar 2008].

Function:
Component of the sarcomere that tethers together nebulin (skeletal muscle) and nebulette (cardiac muscle) to alpha-actinin, at the Z lines.

Subunit:
Interacts with TTN/titin, NEB, NEBL, ACTN2 and CARP.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Note=Bound to sarcomere both at the Z-line periphery and in the central I-band region.

Tissue Specificity:
Expressed in adult skeletal muscle and fetal heart.

Similarity:
Belongs to the myotilin/palladin family.
Contains 5 Ig-like (immunoglobulin-like) domains.

Database links:

Entrez Gene: 84665 Human

Omim: 608517 Human

SwissProt: Q86TC9 Human

Unigene: 55205 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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