Rabbit Anti-Syndecan 3/FITC Conjugated antibody

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N-syndecan; Sdc3; SDC3_HUMAN; SDCN; SYND3; syndecan proteoglycan 3; Syndecan-3.

Cat:

SL15503R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Syndecan 3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009].

Function:
Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed in the nervous system, the adrenal gland, and the spleen.

Post-translational modifications:
O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules (Probable).

Similarity:
Belongs to the syndecan proteoglycan family.

Database links:

Entrez Gene: 9672 Human

Entrez Gene: 20970 Mouse

Entrez Gene: 116673 Rat

Omim: 186357 Human

SwissProt: O75056 Human

SwissProt: Q64519 Mouse

SwissProt: P33671 Rat

Unigene: 158287 Human

Unigene: 206536 Mouse

Unigene: 10504 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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