Rabbit Anti-PCSK4/FITC Conjugated antibody

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PC4; PCSK4; PCSK4_HUMAN; Proprotein convertase 4; Proprotein convertase PC4; Proprotein convertase subtilisin/kexin type 4.

Cat:

SL15501R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human PCSK4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

70kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
PCSK4 is a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Function:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Placenta.

Similarity:
Belongs to the peptidase S8 family. Furin subfamily.
Contains 1 FU (furin-like) repeat.

Database links:

Entrez Gene: 54760 Human

Omim: 600487 Human

SwissProt: Q6UW60 Human

Unigene: 46884 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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