Rabbit Anti-VAMP1+VAMP2+VAMP3/FITC Conjugated antibody

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VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Ve

Cat:

SL10427R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human VAMP-1+2+3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

25kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].

Function:
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Subunit:
Interacts with VAPA and VAPB.

Subcellular Location:
Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome.

Tissue Specificity:
Nervous system, skeletal muscle and adipose tissue.

Similarity:
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

Database links:

Entrez Gene: 6843 Human

Entrez Gene: 6844 Human

Entrez Gene: 9341 Human

Entrez Gene: 22317 Mouse

Entrez Gene: 22318 Mouse

Entrez Gene: 22319 Mouse

Entrez Gene: 4963 Rat

Entrez Gene: 25624 Rat

Entrez Gene: 29528 Rat

Omim: 185176 Human

Omim: 185881 Human

Omim: 603657 Human