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Rabbit Anti-IER2/FITC Conjugated antibody
background:
IER2 is a 223 amino acid protein belonging to the immediate early response (IER) family. IER proteins are the first gene products to be induced during growth stimulation and/or arrest. IER2 expression can be induced by growth factors,12-O-tetradecanoylphorbol-13-acetate (TPA) or Okadaic acid. The coding region of IER2 contains regions of similarity to the transcription factor proteins that are encoded by the Jun oncogene family, possibly indicating a role for IER2 in transcription regulation. Further evidence for this role includes a GUUUG sequence in the 3’ flanking region of IER2, which is believed to be a mRNA degradation signal similar to those found in transcription regulators.
Similarity:
Belongs to the IER family.
Database links:
Entrez Gene: 9592 Human
SwissProt: Q9BTL4 Human
Unigene: 501629 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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