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Rabbit Anti-IFFO/FITC Conjugated antibody
background:
Intermediate filaments are composed of two-chain, a-helical, coiled-coil molecules arranged on an imperfect helical lattice. They have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is a general marker of cells originating in the mesenchyme and is frequently co-expressed with other members of the intermediate filament family, such as the cytokeratins, in certain neoplasms. Vimentin and Desmin, a related class III intermediate filament, are both expressed during skeletal muscle development. Desmuslin links Desmin to the extracellular matrix and provides structural support in muscle. HOM-TES-103, also known as intermediate filament family orphan 1 (IFFO1), is a 559 amino acid protein that belongs to the intermediate filament family. Ubiquitously expressed, HOM-TES-103 exists as seven alternatively spliced isoforms.
Tissue Specificity:
Ubiquitously expressed.
Similarity:
Belongs to the intermediate filament family.
Database links:
Entrez Gene: 25900 Human
Entrez Gene: 64678 Mouse
Entrez Gene: 362437 Rat
Omim: 610495 Human
SwissProt: Q0D2I5 Human
SwissProt: Q8BXL9 Mouse
SwissProt: D3ZWQ2 Rat
Unigene: 15243 Human
Unigene: 129415 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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