Rabbit Anti-IGKV A18/FITC Conjugated antibody

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IGKV A18; Kappa light chain variable region; A2NJV5_HUMAN; Immunoglobulin kappa variable 2-29; A18; A18b; IGKV; IGKV229; IGKV2-29; IGVK-A18; immunoglobulin kappa variable 2-29 (gene/pseudogene).

Cat:

SL15575R-FITC

Species Reactivity：

(predicted: Human,Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human Immunoglobulin kappa variable 2-29

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

13kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:2920447). Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called SLV(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.

Subunit:
Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked.

Subcellular Location:
Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}.
Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}.

Database links:

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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