Rabbit Anti-PRSS2/FITC Conjugated antibody

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Anionic trypsinogen; EC 3.4.21.4; MGC111183; MGC120174; Protease serine 2 preproprotein; Protease, serine, 2 (trypsin 2); Protease, serine, 2; Protease, serine, 2, preproprotein; Prss2; Serine protease 2; TRY2; TRY2_HUMAN; TRY8; TRYP2; Trypsin 2; Trypsin

Cat:

SL10501R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human PRSS2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

25kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008].

Function:
In the ileum, may be involved in defensin processing, including DEFA5.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Expressed in Paneth cells, at the base of small intestinal crypts.

Post-translational modifications:
Sulfated on tyrosine.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 5645 Human

Omim: 601564 Human

SwissProt: P07478 Human

Unigene: 449281 Human

Unigene: 728780 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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