Rabbit Anti-valyl tRNA/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-valyl tRNA/FITC Conjugated antibody

SYVM_HUMAN; Valine--tRNA ligase, mitochondrial; Valyl-tRNA synthetase; ValRS; Valyl-tRNA synthetase-like; valyl tRNA; VARS2; KIAA1885; VARS2L; VARSL.

Cat:

SL10504R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human vars2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

115kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
ValRS (valyl-tRNA synthetase), also known as Protein G7a, belongs to the class-I aminoacyl-tRNA synthetase family that includes the related proteins, LeuRS and IleRS. These proteins are large monomeric proteins and play a major role in catalyzing the aminoacylation of tRNA by their cognate amino acid. ValRS joins Val to tRNA(Val) at its synthetic active site. At its CP1 editing active site, ValRS hydrolyzes or deacylates tRNA(Thr) that is incorrectly joined to Val. ValRS forms aggregates with EF-1 (elongation factor 1) and, via this complex, catalyzes the aminoacylation of tRNA and its transfer to EF-1. In addition, ValRS may be regulated by PKSLCdependent phosphorylation.

Subcellular Location:
Mitochondrion (Potential).

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

Database links:

Entrez Gene: 7407 Human

Entrez Gene: 25009 Rat

Omim: 192150 Human

SwissProt: P26128 Human

SwissProt: Q04462 Rat

Unigene: 520026 Human

Unigene: 12314 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall