background:
KDM2 / JHD1 is a JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe.
Function:
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Does not demethylate H3 'Lys-4' nor 'Lys-79'. {ECO:0000269|PubMed:16362057}.
Subcellular Location:
Nuclear.
Similarity:
Belongs to the JHDM1 histone demethylase family.
Database links:
Entrez Gene: 856777 Saccharomyces cerevisiae
SwissProt: P40034 Saccharomyces cerevisiae
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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