Home > Product > Antibody > Rabbit Anti-SPANXB1/FITC Conjugated antibody
Cancer/testis antigen 11.2; Cancer/testis antigen family 11, member 2; CT11.2; hCG2036708; Nuclear associated protein SPAN Xb; Nuclear-associated protein SPAN-Xb; Nuclear-associated protein SPAN-Xf; SPAN Xb protein; SPAN Xf; SPANX; SPANX B; SPA
Cat:
SL13618R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human SPANXB1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
12kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
A variety of morphological and molecular changes are required for mature spermatozoa formation. These steps are temporally guided by the transcription and translation of several testis-specific genes. SPANX (sperm protein associated with the nucleus, X-linked) family members are sperm- and testis-specific proteins containing between 97-103 amino acids, whose genes form a cluster on chromosome X. Sharing a high level of sequence similarity, SPANX-A, -B, -C, -D and -E localize to both cytoplasm and nucleus where they are associated with nuclear craters. SPANX-B (Sperm protein associated with the nucleus on the X chromosome B/F) is a 103 amino acid protein that is detected in round and elongating spermatids.

Subcellular Location:
Cytoplasm. Nucleus. Associated with nuclear craters.

Tissue Specificity:
Detected in testis and sperm.

Similarity:
Belongs to the SPAN-X family.

Database links:

Entrez Gene: 171490 Human

Entrez Gene: 100133171 Human

Entrez Gene: 728695 Human

Omim: 300669 Human

SwissProt: Q9NS25 Human

Unigene: 434105 Human

Unigene: 711489 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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