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Rabbit Anti-FA20A/FITC Conjugated antibody
background:
FA20A belongs to the FAM20 family. All FAM20 proteins contain putative conserved signal sequences as well as a conserved C terminal domain. FA20A is a secreted glycoprotein. It has been found in EML and MPRO cell lines, with low levels in undifferentiated cells. FA20A is induced during maturation to promyelocyte stage of neutrophil differentiation and decreased during neutrophil terminal differentiation.
Subcellular Location:
Secreted
Tissue Specificity:
Highly expressed in lung and liver. Intermediate levels in thymus and ovary.
Post-translational modifications:
N-glycosylated (By similarity).
DISEASE:
Amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS) [MIM:614253]: An autosomal recessive condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal radiolucencies, and unerupted teeth. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the FAM20 family.
Database links:
Entrez Gene: 54757 Human
Omim: 611062 Human
SwissProt: Q96MK3 Human
Unigene: 268874 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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