Rabbit Anti-AP1M2/FITC Conjugated antibody

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Adaptor protein complex AP-1 mu-2 subunit; Adaptor protein complex AP1 mu2 subunit; Adaptor related protein complex 1 mu2 subunit; Adaptor-related protein complex 1 mu-2 subunit; AP mu chain family member mu1B; AP-1 complex subunit mu-2; AP-mu chain

Cat:

SL13638R-FITC

Species Reactivity：

(predicted: Human,Mouse,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human AP1M2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

48kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Subcellular Location:
Golgi apparatus. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Post-translational modifications:
Phosphorylation of membrane-bound AP1M1/AP1M2 increases its affinity for sorting signals.

Similarity:
Belongs to the adaptor complexes medium subunit family.
Contains 1 MHD (mu homology) domain.

Database links:

Entrez Gene: 10053 Human

Entrez Gene: 515766 Cow

Entrez Gene: 11768 Mouse

Omim: 607309 Human

SwissProt: Q3SYW1 Cow

SwissProt: Q9Y6Q5 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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