Rabbit Anti-PACSIN3/FITC Conjugated antibody

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Endophilin 1; Endophilin I; FLJ17861; OTTHUMP00000234262; OTTHUMP00000234263; OTTHUMP00000234264; PACN3_HUMAN; Pacsin3; Protein kinase C and casein kinase substrate in neurons 3; Protein kinase C and casein kinase substrate in neurons protein 3;

Cat:

SL13659R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PACSIN3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

48kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).

Function:
May play a role in vesicle formation and transport.

Subcellular Location:
Cytoplasm. Cell membrane. Detected at the inner aspect of the plasma membrane in cells or myotubes.

Tissue Specificity:
Expressed in heart and skeletal muscle, lung, kidney, adrenal gland and placenta.

Post-translational modifications:
Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).

Similarity:
Belongs to the PACSIN family.
Contains 1 FCH domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 29763 Human

Entrez Gene: 80708 Mouse

Omim: 606513 Human

SwissProt: Q9UKS6 Human

SwissProt: Q99JB8 Mouse

Unigene: 334639 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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