Rabbit Anti-PCDH10/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-PCDH10/FITC Conjugated antibody

DKFZp761O2023; KIAA1400; MGC133344; OL PCDH; Ortholog of OL pcdh; OTTHUMP00000220001; PCD10_HUMAN; PCDH10; PCDH19; Protocadherin 10; Protocadherin-10.

Cat:

SL13723R-FITC

Species Reactivity：

(predicted: Human,Pig,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PCDH10

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

110kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH10 (protocadherin 10), also known as PCDH19 or OL-PCDH, is a 1,040 amino acid single-pass type I membrane protein that contains six cadherin domains and one transmembrane domain. Expressed at moderate levels in brain, ovary and testis and present at lower levels in all other tissues, PCDH10 functions as a calcium-dependent cell-adhesion protein that may function as a tumor suppressor. When underexpressed, PCDH10 is associated with the progression of various carcinomas, including gastric cancer.

Function:
Potential calcium-dependent cell-adhesion protein.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Moderately expressed in all regions of the brain examined, as well as in testis and ovary, and low expression in all other tissues tested.

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 57575 Human

Entrez Gene: 531875 Cow

Entrez Gene: 18526 Mouse

Omim: 608286 Human

SwissProt: Q9P2E7 Human

Unigene: 192859 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall