Rabbit Anti-2 Cys Peroxiredoxin/FITC Conjugated antibody

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Antioxidant enzyme; Peroxiredoxin 1; Peroxiredoxin 2; Peroxiredoxin 3; Peroxiredoxin 4; Peroxiredoxin 5; Peroxiredoxin 5 mitochondrial; PLP; PMP20; PRDX1; PRDX2; PRDX3; PRDX4; PRDX5; PRX V; Thioredoxin reductase.

Cat:

SL7356R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Pig,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human 2 Cys Peroxiredoxin

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

17kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Peroxiredoxin (Prx) is a growing peroxidase family whose mammalian members are involved in cell proliferation, differentiation, and apoptosis. There are many isoforms(about 50 proteins), known on the basis of amino acid sequence homology, particularly the amino-terminal region containing an active site cysteine residue. The thiol-specific antioxidant activity is distributed throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2 Cys, atypical 2 Cys Prx, and 1 Cys Prx. Except PrxVI belonging to the 1 Cys Prx subgroup, the other five 2 Cys Prx isotypes share the thioredoxin dependent peroxidase(TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20–30 kilodaltons in molecular size and vary in subcellular localization:PrxI, II and VI in cytosol, PrxIII in mitochondria, PrxIV in ER and secretion, PrxV showing complicated distribution including peroxisome, mitochondria and cytosol.

Subcellular Location:
Cytoplasmic.

Database links:

Entrez Gene: 10549 Human

Entrez Gene: 10935 Human

Entrez Gene: 5052 Human

Entrez Gene: 7001 Human

Entrez Gene: 22898 Rat

SwissProt: P30044 Human

SwissProt: P30048 Human

SwissProt: P32119 Human

SwissProt: Q06830 Human

SwissProt: Q13162 Human

SwissProt: Q9R063 Rat

Unigene: 502823 Human

Unigene: 2944 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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