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Rabbit Anti-APR3/FITC Conjugated antibody
background:
This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009]
Function:
Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.
Subunit:
Interacts with NELL1; the interaction promotes osteoblastic differentiation and mineralization.
Subcellular Location:
Cell membrane; Single pass membrane protein.
Tissue Specificity:
Weakly expressed in hematopoietic cell lines.
Similarity:
Contains 1 EGF-like domain.
Database links:
Entrez Gene: 51374 Human
SwissProt: Q6UW56 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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