Rabbit Anti-CELA1/FITC Conjugated antibody

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CELA 1; CELA1; CELA1_HUMAN; Chymotrypsin like elastase family member 1; Chymotrypsin-like elastase family member 1; ELA1; Elastase 1; Elastase 1 pancreatic; Elastase-1; OTTHUMP00000236087.

Cat:

SL13828R-FITC

Species Reactivity：

(predicted: Human,Rat,Dog,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human CELA1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

28kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]

Function:
Acts upon elastin.

Subcellular Location:
Secreted.

Tissue Specificity:
Skin; not expressed in pancreas.

Similarity:
Belongs to the peptidase S1 family. Elastase subfamily. Contains 1 peptidase S1 domain.

Database links:

Entrez Gene: 1990 Human

Entrez Gene: 24331 Rat

Omim: 130120 Human

SwissProt: Q9UNI1 Human

SwissProt: P00773 Rat

Unigene: 348395 Human

Unigene: 6044 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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