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Rabbit Anti-CEP192/FITC Conjugated antibody
background:
Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication.
Subcellular Location:
Required for mitotic centrosome and spindle assembly. Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication.
Post-translational modifications:
Hydroxylation by PHD1/EGLN2 at Pro-1717 promotes ubiquitination.
Ubiquitinated by a SCF(SKP2) complex following proline hydroxylation.
Database links:
Entrez Gene: 55125 Human
SwissProt: Q8TEP8 Human
Unigene: 100914 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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