Rabbit Anti-CHES1/FITC Conjugated antibody

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C14orf116; Checkpoint suppressor 1; CHES1; Forkhead box protein N3; Foxn3; FOXN3_HUMAN; FXN3; FXN3; PRO1635.

Cat:

SL13899R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CHES1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

54kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]

Function:
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).

Subcellular Location:
Nucleus.

Similarity:
Contains 1 fork-head DNA-binding domain.

Database links:

Entrez Gene: 1112 Human

Entrez Gene: 71375 Mouse

Entrez Gene: 314374 Rat

Omim: 602628 Human

SwissProt: O00409 Human

SwissProt: Q499D0 Mouse

Unigene: 434286 Human

Unigene: 621371 Human

Unigene: 341972 Mouse

Unigene: 392143 Mouse

Unigene: 448530 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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