Home > Product > Antibody > Rabbit Anti-Choline kinase alpha/FITC Conjugated antibody
CHETK alpha; CHETK-alpha; CHK; CHKA; CK; CKI; EK; Ethanolamine kinase; CHKA_HUMAN.
Cat:
SL13921R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human Choline kinase alpha
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
52kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
The dominant pathway for biosynthesis of phosphatidylcholine occurs through the CDP-choline pathway. Choline kinase alpha (CHK) is the first enzyme in the pathway and may thereby play an upstream regulatory role in lipid transport and metabolism. CHK additionally catalyzes phosphorylation of ethanolamine.

Subunit:
Heterodimer with CHKB (By similarity). Homodimer.

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the choline/ethanolamine kinase family.

Database links:

Entrez Gene: 1119 Human

Entrez Gene: 12660 Mouse

Entrez Gene: 29194 Rat

Omim: 118491 Human

SwissProt: P35790 Human

SwissProt: O5964 Mouse

SwissProt: Q01134 Rat

Unigene: 77221 Human

Unigene: 225505 Mouse

Unigene: 2205 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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