Rabbit Anti-CORO7/FITC Conjugated antibody

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Clipin-E; CORO6; CORO7_HUMAN; Coronin, actin binding protein 6; Coronin-6; Coronin-like protein E; FLJ14871; PP1009; PP1782; PP1881.

Cat:

SL13999R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CORO7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

101kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]).[supplied by OMIM, Mar 2008]

Function:
May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi.

Subcellular Location:
Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle. Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.

Post-translational modifications:
The membrane-associated form is phosphorylated on tyrosine residues.

Similarity:
Belongs to the WD repeat coronin family.
Contains 8 WD repeats.

Database links:

Entrez Gene: 79585 Human

Entrez Gene: 78885 Mouse

Entrez Gene: 192276 Rat

Omim: 611668 Human

SwissProt: P57737 Human

SwissProt: Q9D2V7 Mouse

SwissProt: O35828 Rat

Unigene: 437957 Human

Unigene: 325512 Mouse

Unigene: 2768 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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