Home
>
Product
>
Antibody
>
Rabbit Anti-GCDFP15/FITC Conjugated antibody
background:
Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
Subunit:
Monomer. Interacts with AZGP1.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed in pathological conditions of the mammary gland and in several exocrine tissues, such as the lacrimal, salivary, and sweat glands.
Similarity:
Belongs to the PIP family.
Database links:
Entrez Gene: 5304 Human
Entrez Gene: 18716 Mouse
Omim: 176720 Human
SwissProt: P12273 Human
Unigene: 99949 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|