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Rabbit Anti-COX7B/FITC Conjugated antibody
background:
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIb, which is highly similar to bovine COX VIIb protein and is found in all tissues. This gene may have several pseudogenes on chromosomes 1, 2, 20 and 22. [provided by RefSeq, Jun 2011]
Function:
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the cytochrome c oxidase VIIb family.
Database links:
Entrez Gene: 1349 Human
Entrez Gene: 66142 Mouse
Entrez Gene: 303393 Rat
Omim: 603792 Human
SwissProt: P24311 Human
SwissProt: P56393 Mouse
SwissProt: P80431 Rat
Unigene: 522699 Human
Unigene: 197728 Mouse
Unigene: 2026 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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