Rabbit Anti-CPEB2/FITC Conjugated antibody

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CPE binding protein 2; CPE BP2; CPEB 2; CPEBP2; Cytoplasmic polyadenylation element binding protein 2; hCPEB 2; hCPEB2; CPEB2_HUMAN.

Cat:

SL14019R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CPEB2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

65kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
CPEB2, (Cytoplasmic polyadenylation element-binding protein 2), belongs to the RRM CPEB family and contains 2 RRM (RNA recognition motif) domains. It may bind poly(U) RNA oligomers. It may play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. There are 7 named isoforms [FASTA] produced by alternative splicing.

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 132864 Human

Entrez Gene: 231207 Mouse

Entrez Gene: 72949 Rat

Omim: 610605 Human

SwissProt: Q7Z5Q1 Human

SwissProt: Q812E0 Mouse

Unigene: 656937 Human

Unigene: 162283 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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