Rabbit Anti-TRH/FITC Conjugated antibody

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Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF; TRH_HUMAN.

Cat:

SL10593R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated human TRH (pGlu-His-Pro-Amide)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

24kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013].
（L-Pyroglutamyl-L-histidyl-L-prolinamide）pGlu-His-Pro Amide, C18H26N6O6

Function:
Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets.

Subcellular Location:
Secreted.

Tissue Specificity:
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).

Similarity:
Belongs to the TRH family.

Database links:

Entrez Gene: 1440 Human

Entrez Gene: 22044 Mouse

Entrez Gene: 25569 Rat

Omim: 275120 Human

SwissProt: P20396 Human

SwissProt: Q62361 Mouse

SwissProt: P01150 Rat

Unigene: 1363 Mouse

Unigene: 22 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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