Rabbit Anti-CR1L/FITC Conjugated antibody

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Complement C4b-binding protein CR-1-like protein; Complement component receptor 1-like protein; CR1L.

Cat:

SL14042R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from human CR1L

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

64kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
CR16 is a 483 amino acid proline-rich cytoplasmic protein that is thought to regulate cytoskeletal organization. A member of both the verprolin and Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) families, CR16 colocalizes with N-WASP (Neuronal Wiskott-Aldrich syndrome protein) in tips of growth cone filopodia, primary hippocampal neurons and Sertoli cell-spermatid junctions. CR16 and N-WASP functionally interact to influence spermatogenesis. CR16 is predominantly expressed in brain and testis, contains one WH2 domain, a KLKR motif, three profilin-binding motifs and is encoded by a gene that maps to human chromosome 7p15.1.

Function:
Interacts with iC4 (methylamine-treated C4) but not for iC3 (methylamine-treated C3). Belongs to the receptors of complement activation (RCA) family. Contains 8 Sushi (CCP/SCR) domains.

Subcellular Location:
Cytoplasm. Membrane. Secreted. Note: Predominantly found in association with the membrane fraction, but also located in the cytoplasm and in the supernatant.

Database links:

Entrez Gene: 1379 Human

Omim: 605886 Human

SwissProt: Q2VPA4 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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