Rabbit Anti-Creatine Kinase MB/FITC Conjugated antibody

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CK-MB; B-CK; brain creatine kinase; CKBB; CKMB; CKMM; creatine kinase B; creatine kinase brain; creatine kinase M; Creatine kinase MB; Creatine Kinase MB type; creatine kinase muscle; M-CK; creatine kinase-M/B; KCRB_HUMAN; muscle creatine kinase.

Cat:

SL14049R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human Creatine Kinase MB

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

Function:
Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.

Subcellular Location:
Cytoplasmic and Mitochondrial

Similarity:
Belongs to the ATP:guanido phosphotransferase family.
Contains 1 phosphagen kinase SLCterminal domain.
Contains 1 phosphagen kinase N-terminal domain.

Database links:

Entrez Gene: 1152 Human

Entrez Gene: 1158 Human

Omim: 123310 Human

SwissProt: P06732 Human

SwissProt: P12277 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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