Home > Product > Antibody > Rabbit Anti-CREB5/FITC Conjugated antibody
cAMP response element binding protein 5; cAMP response element binding protein CRE Bpa; cAMP response element-binding protein CREBPa; cAMP responsive element binding protein 5; cAMP responsive element binding protein 5 isoform alpha; cAMP-responsive eleme
Cat:
SL14053R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Chicken,Dog,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human CREB5
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
57kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Function:
Binds to the cAMP response element and activates transcription.

Subunit:
Binds DNA as a homodimer or as a heterodimer with JUN or ATF2/CREBP1.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family.
Contains 1 bZIP domain.
Contains 1 C2H2-type zinc finger.

Database links:

Entrez Gene: 9586 Human

Entrez Gene: 231991 Mouse

Entrez Gene: 500131 Rat

SwissProt: Q02930 Human

SwissProt: Q8K1L0 Mouse

Unigene: 437075 Human

Unigene: 32228 Mouse

Unigene: 210235 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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